Honokiol - 200mg / 60 capsules

Honokiol is a small-molecule polyphenol isolated from the genus Magnolia. It is accompanied by other related polyphenols, including magnolol, with which it shares certain healing properties and pleiotropic effects. Recently, honokiol has been found to have antiangiogenic, antiinflammatory, and antitumor properties in preclinical models, without appreciable toxicity.

Honokiol has pleiotropic effects involving the influence of a single gene on multiple biological traits : sirt3 activation. The honokiol molecule has demonstrated the ability to influence the formation and appearance of biological traits. The compound also has the ability to cross the blood-brain barrier to protect neurons from potential harm. Modern researchers are focusing on honokiol’s neuroprotective and chemotherapeutic actions.

Dynveo Honokiol is extracted from Magnolia bark and standardized to a minimum of 90% Honokioland and a minimum of 1% of Magnolol.

More details

  • HO20060

$45.00

Honokiol is a small molecule with broad antitumor activity. Unlike many other natural products, honokiol exhibits a desirable spectrum of bioavailability. The development of other polyphenolic agents has been hindered by poor absorption and rapid excretion (i.e., curcumin). Honokiol does not have this disability, in that significant systemic levels of honokiol can be obtained in preclinical models and that honokiol can cross the blood–brain barrier. In this review, we demonstrate that honokiol has two distinct mechanisms of action. The first one is through inhibition of ras signaling, and appears to be most active in tumors with defective p53 function. The second one is through induction of cyclophilin D and activation of the mitochondrial transition pore. Honokiol appears to have distinct activities against tumors with mutant p53, through inhibition of ras-phospholipase D activation, and tumors with wild-type p53, through induction of cyclophilin D and potentiation of the mitochondrial transition pore.

Honokiol also exhibits antiviral activity against HIV, perhaps through inhibition of NF-κB signaling. Thus, honokiol may be useful in the setting of immunocompromise. Future clinical trials should be carried out combining honokiol with conventional chemotherapy, and increased efficacy might be observed through alleviation of chemotherapy-induced NF-κB activation. This knowledge is required for the development of future analogues, which may target either of these pathways, and for the development of clinical trials using honokiol and honokiol analogues, in which p53 status may play a key role in efficacy.

  • - Anti-aging
  • - antitumor
  • - sirt3 booster

As a dietary supplement, take one (1) veggie capsule per day with water, or as recommended by a healthcare practitioner.

For 1 capsule: 200 mg honokiol dry extract 90% pure

Other ingredients : Non-GMO vegetable capsule (hypromellose). Made without fillers. No ingredients others than those listed.

Dynveo® extracted Honokiol using only "green solvant" : a combination of ethanol / water and we dried it without harsh chemical added. This is the most natural and chemical free version you can have. This product is also 100% guaranteed without excipient or fillers. Each capsule contains only the dry honokiol extract.

-> Dynveo Warranty: No excipients and no fillers (each vegetarian capsule contains only the powdered extract). Guaranteed non-irradiated; non-GMO; and naturally without yeast, gluten, milk derivatives, coloring and preservatives.

Vegan product (100% vegan and not tested on animals)

TEST
  • - Anti-aging
  • - antitumor
  • - sirt3 booster

As a dietary supplement, take one (1) veggie capsule per day with water, or as recommended by a healthcare practitioner.

TEST

For 1 capsule: 200 mg honokiol dry extract 90% pure

Other ingredients : Non-GMO vegetable capsule (hypromellose). Made without fillers. No ingredients others than those listed.

Dynveo® extracted Honokiol using only "green solvant" : a combination of ethanol / water and we dried it without harsh chemical added. This is the most natural and chemical free version you can have. This product is also 100% guaranteed without excipient or fillers. Each capsule contains only the dry honokiol extract.

-> Dynveo Warranty: No excipients and no fillers (each vegetarian capsule contains only the powdered extract). Guaranteed non-irradiated; non-GMO; and naturally without yeast, gluten, milk derivatives, coloring and preservatives.

Vegan product (100% vegan and not tested on animals)

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